Matthew D. Barber, MD

AOC Dr. Barber
Dr. Barber is a fellowship-trained specialist in joint replacement surgery of the knee and hip. His commitment to continuous learning and education helps him to select the best techniques and technologies to achieve great outcomes for his patients. Because of his experience with advanced technologies such as custom implants, robotics and computer navigation; Dr. Barber is sought out by patients throughout the Southeast region.



Area of Specialty

  • Joint Replacement
  • Knee and Hip


  • Board Certified by the American Board of Orthopaedic Surgery


  • Arizona Institute for Bone and Joint Disorders, Pheonix, AZ - Joint Replacement


  • Residency; University of South Alabama Hospitals, Mobile, AL - Orthopaedic Surgery
  • University of South Alabama College of Medicine, Mobile, AL - Doctor of Medicine
  • University of South Alabama, Mobile, AL - Bachelor of Science in Biomedical Sciences


  • Alabama Orthopaedic Society
  • American Academy of Orthopaedic Surgeons
  • American Association of Hip and Knee Surgeons
  • Medical Association of the State of Alabama
  • Medical Society of Mobile County

Hospital Affiliations

  • Mobile Infirmary Medical Center
  • Springhill Medical Center

Additional information, articles and links about Dr. Barber


Click to view Matthew D. Barber videos


"Very professional"

— Henry DeVasher

Rating: 5 Star

"Dr Barber is the BEST Dr ever for my total Conformis knee replacement on November 26th 2018. I was up walking next morning. It's unreal the pain is gone that l lived with for 30 years. I'm Thankfull to God for sending Dr Barber in my life plus before surgery he prayed. Loved that, it made all the difference. Dr Barber is a wonderful dr along with everyone in his office! ? Love them all."

— Debby Butler

Rating: 5 Star

"Excellent surgery and after surgery pain management. Outstanding communications before surgery to insure all elements were addressed and smooth pre-op. Good follow up after hospital release. I will recommend Dr. Barber to all friends and family for any orthopedic needs."

— John Leech

Rating: 5 Star

"In my opinion, Dr Barber is the best orthopedic surgeon providing joint replacements in the Mobile area. Prior to surgery he took time to answer questions that my husband and I had. At three weeks out, am pleased with my postoperative progress so far and looking forward to ambulatung with ease in the near future!!"

— Barbara Naman

Rating: 5 Star

"Doctor Barber did total knee replacement on my left knee in December 2015. Since then my knee is as good as new, I’m thankful to have use of my leg again. My right knee was replaced in 2006 by a different doctor, and it has never been right. I wish i had found Dr. Barber in time to have that knee done by him also. Just prior to beginning my surgery, Dr. Barber came to my bedside, laid hands on me and prayed for God’s guidance through the surgery. It is a blessing to have a Godly physician."

— Brnnie Green

Rating: 5 Star

"Dr. Barber replaced my left knee and I can walk without a cane and I feel so much better. He prays with you before surgery and I liked that. I would recommend him to anyone and if I had to get another knee surgery it would be Dr. Barber.ii"

— Annie Reed

Rating: 4 Star

"Very professional and skilled. He was very thorough."

— Anonymous

Rating: 5 Star

"He’s the knee replacement expert. I had both knees replaced at the same time. Perfect results on both. I walked the night of my surgery. Without assistance in one week. He’s the Best!!!!"

— Carolyn Sawyer

Rating: 5 Star

"I have been an established patient for years for osteoarthritis of joints, more particularly, my knees. I underwent total knee replacement last November. Dr. Barber is not only a fine physcian, but I have also had the pleasure of knowing his family and I can speak highly of his integrity."

— Mary

Rating: 5 Star

"Dr Barber and his staff are top notch! I highly recommend him to everyone."

— James

Rating: 5 Star